Olink Explore HT — Olink® (2024)

Olink Explore HT

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Capture true biological insights with proven specificity. At any scale.

Olink® Explore HT

Perform high-throughput biomarker discovery with ease to understand disease at the protein level.

Unprecedented power

Olink Explore HT is the next-generation solution for high-throughput proteomics. Run in your own lab, access via our worldwide network of service providers, or at Olink Analysis Services.

Overview

  • Proteins

    5,400+With proven specificity

  • Sample

    2 µLPlasma, serum & more

  • Specificity

    99.5%Negligible cross-reactivity

  • Throughput

    4xIncrease over previous generation

  • Dynamic range

    fg-mg/mL10 logs

  • Readout

    NGSAutomated workflow

Developed for specificity, validated for quality

Our dual-recognition, DNA-coupled technology delivers industry-leading specificity, eliminating wrong targets, misinterpretation and wasted resources. Every assay undergoes a rigorous validation process, ensuring quality data you can trust.

Carefully curated to provide deeper biological insights

Our protein selection strategy focuses on functional, actionable, druggable, and circulating proteins. Drawn from protein annotations, publications, clinical trials, approved therapies, and researcher requests.

Download the biomarker list

Biomarker coverage

  • Intelligently selected

    5,400+Validated protein assays

  • High coverage

    +85%More than previous generation

  • Full top-level coverage

    100%Of top-level pathways

Realize any project you can imagine

Olink Explore HT is designed for outstanding performance at any scale of protein biomarker discovery, from tens to millions of samples. This scalability is enabled by a streamlined, automated workflow and a comprehensive software suite, all optimized for high-throughput data acquisition.

Workflow

4x faster

Compared to previous generation

Project completion

Analyze 50,000 samples in 12 weeks

With two instrumentation lines

Olink Explore HT — Olink® (1)

Throughput

11 million

datapoints per week with
 a single instrumentation line

Revealing the truth of human disease. Protein by protein.

Olink’s trusted proteomics solutions are helping to bridge the gap between genomics and human diseases. Population-scale studies are increasingly being used to provide comprehensive views of protein expression patterns across the diversity of human biology. Olink technology has been applied to one of the world’s largest proteomic health studies, revealing biomarkers that can predict cancer more than a decade before diagnosis.

Population scaleUK Biobank on Olink InsightAccess the largest collection of next-generation proteomic dataLearn more

Olink Explore enabled the pioneering UK Biobank Pharma Proteomics Project. This ongoing population-scale project, backed by a pharma consortium, applied the Olink Explore platform for proteomic analysis of over 54,000 participants. To date, over 20,000 genetic associations for ~3,000 proteins have been identified, with much more to come. The protein data is freely available in Olink Insight.

Olink Explore HT — Olink® (4)

More data. Less effort.

Accelerate your biomarker discovery with a faster workflow and significant reagent reduction. With Olink Explore HT, we’ve reimagined our packaging, resulting in a 10-fold reduction in boxes and a 6-fold decrease in components. The new NPX Explore HT software suite simplifies data analysis, allowing you to derive actionable biological findings faster.

Efficiency

  • Data points

    7x moreto reveal additional biological insights

  • Components

    6x fewerto save time and resources

Scalability and flexibility in data processing

Experience unmatched scalability and flexibility in data processing. Our custom software ensures consistent data across platforms, allowing you to operate and access your data anytime, anywhere –be it desktop, CLI, office, or lab. We provide advanced tools and features that simplify data understanding and empower you to make informed decisions about data re-runs.

NPX Explore 3072 & HT

Desktop analysis software

NPX Explore 3072 & HT is equipped with product-specific views and allows you to easily visualize data, detect potential errors in lab workflows – ensuring data you can trust.

NPX Explore 3072 & HT CLI

Command-line interface

We offer a powerful CLI to complement our desktop software, enabling efficient large-scale data set analysis. It integrates seamlessly with laboratory LIMS and extends to the downstream data analysis pipeline.

Quality control

Built-in QC

A new integrated software concept for better, faster quality control, minimizing manual steps, and optimizing your data pipeline.

Amplify discovery.
Advance genomics.

When you combine proteomic data with genomic datasets, your statistical significance skyrockets. Olink data is designed for maximum transparency and comparability – whether you’re investigating novel drug targets or digging deeper into existing sample collections to repurpose on-market therapies.

Population-scale proteogenomicsAdding proteomics to genetic datasets brings genomics closer to phenotype, opening up new possibilities for exploring biological pathways and their interconnections.Learn more

Documents

Below you will find a few documents related to this product. For the complete documentation including SDS, user manuals, technical notes and more, visit the documents section.

DocumentsTypeFile
Advancing biomarker discovery in ovarian cancer with Olink® Explore HT

Case studies

Download PDF
PEA: Exceptional specificity in a high multiplex format

White paper

A flexible platform that accelerates your research

Olink’s scalable technology provides optimized solutions for every stage of the biomarker workflow, from high-throughput discovery through validation and clinical utility.

Get help choosing.Talk to a Specialist

Olink Explore HT — Olink® (7)

Olink Target 96

Target specific disease areas or key biological processes with multiplex immunoassay panels.

Proteins

1,100+On 15 targeted panels

Sample

1 µLPlasma, serum & more

Learn more

Olink Explore HT — Olink® (8)

Olink Target 48

Extensively validated and carefully selected biomarkers for a comprehensive view of cytokine signaling and inflammatory processes.

Proteins

89On 2 panels

Sample

1 µLPlasma, serum & more

Learn more

Olink Explore HT — Olink® (9)

Olink Flex

Run individually tailored studies by combining up to 21 biomarkers from our extensive library with minimal sample volume.

Proteins

~200Pre-validated assays

Sample

1 µLPlasma, serum & more

Learn more

Olink Explore HT — Olink® (10)

Olink Focus

Custom designed panels that transition you from biomarker discovery to clinical utility of protein signatures.

Proteins

Up to 21Pre-validated assays

Sample

1 µLPlasma, serum & more

Learn more

Olink Explore HT — Olink® (2024)
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